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It is used against infections caused by Enterococcus faecium, Staphylococcus aureus, Streptococcus pneumoniae (pneumonia), Streptococcus pyogenes, Streptococcus agalactiae (skin infections, including diabetic foot infections), Streptococcus pyogenes (skin infections).

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Cell wall thickening is a consistent feature and was recognized well before the first description of clinical VISA isolates (Fig.

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